Role of metallothionein and other antioxidants in scavenging superoxide radicals and their possible role in neuroprotection.

@article{Hussain1996RoleOM,
  title={Role of metallothionein and other antioxidants in scavenging superoxide radicals and their possible role in neuroprotection.},
  author={S Hussain and William Slikker and S. Fatehyab Ali},
  journal={Neurochemistry international},
  year={1996},
  volume={29 2},
  pages={145-52}
}
Based on the inhibition of nitrite formation by generating superoxide from xanthine/xanthine oxidase (X/XO) reaction system, metallothionein (MT) and other sulfhydryl containing amino acids have been selected to test their abilities to scavenge superoxide radicals. Different concentrations of metallothionein and other sulfhydryl containing molecules e.g. cysteine, N-acetyl-cysteine and glutathione, were used to assess superoxide scavenging properties. Metallothionein scavenges superoxide… CONTINUE READING
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