Role of metallothionein against oxidative stress in the mussel Mytilus galloprovincialis.

@article{Viarengo1999RoleOM,
  title={Role of metallothionein against oxidative stress in the mussel Mytilus galloprovincialis.},
  author={Aldo Viarengo and Bruno Burlando and Maria Cavaletto and Barbara Marchi and Enrica Ponzano and J. Blasco},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={1999},
  volume={277 6},
  pages={R1612-R1619}
}
Metallothionein (MT) is a sulfhydryl-rich protein involved mainly in heavy metal homeostasis and detoxification. In this study, the use of the mussel as an experimental model allowed us to test MT antioxidant properties at the molecular, cellular, and organism level. MT induction was achieved by mussel exposure to Cd (200 μg/l) in aquaria for 7 days followed by detoxification in the sea for 28 days. Cd-preexposed and nonexposed mussels were then treated with Fe (300-600 μg/l) in aquaria for 3… CONTINUE READING

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