Role of melatonin supplementation in neurodegenerative disorders.

  title={Role of melatonin supplementation in neurodegenerative disorders.},
  author={Giovanni Polimeni and Emanuela Esposito and Valentina Bevelacqua and Claudio Guarneri and Salvatore Cuzzocrea},
  journal={Frontiers in bioscience},
Neurodegenerative diseases are chronic and progressive disorders characterized by selective destruction of neurons in motor, sensory and cognitive systems. Despite their different origin, free radicals accumulation and consequent tissue damage are importantly concerned for the majority of them. In recent years, research on melatonin revealed a potent activity of this hormone against oxidative and nitrosative stress-induced damage within the nervous system. Indeed, melatonin turned out to be… 

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