Role of melatonin in mood disorders and the antidepressant effects of agomelatine.

Abstract

INTRODUCTION Disturbances of circadian rhythms and sleep play an important role in various types of mood disorders like major depressive disorder (MDD), bipolar depressive disorder (BPD) and seasonal affective disorder (SAD). Malfunctioning of the SCN-pineal-melatonin link has been suggested as the main cause for these disorders. As a rhythm-regulating… (More)

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Cite this paper

@article{Srinivasan2012RoleOM, title={Role of melatonin in mood disorders and the antidepressant effects of agomelatine.}, author={Venkataramanujam Srinivasan and Domenico De Berardis and Samuel D. Shillcutt and Amnon Brzezinski}, journal={Expert opinion on investigational drugs}, year={2012}, volume={21 10}, pages={1503-22} }