Role of matrix metaloproteases in idiopathic pulmonary fibrosis

Abstract

Lung fibrosis is the final common pathway of a large variety of chronic lung disorders, named interstitial lung diseases. The most aggressive form is the idiopathic pulmonary fibrosis [IPF] characterized by alveolar epithelial cell injury/activation, expansion of the fibroblast/myofibroblast population, and the exaggerated accumulation of extracellular… (More)
DOI: 10.1186/1755-1536-5-S1-S9

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