Role of matrix metalloproteinases in non-healing venous ulcers.

  title={Role of matrix metalloproteinases in non-healing venous ulcers.},
  author={Bruno Amato and Guido Coretti and Rita Compagna and Maurizio Amato and Gianluca Buffone and Diego Gigliotti and Raffaele Del Grande and Raffaele Serra and Stefano de Franciscis},
  journal={International wound journal},
  volume={12 6},
Chronic venous ulceration (CVU) of the lower limbs is a common condition affecting 1% of the adult population in Western countries, which is burdened with a high complication rate and a marked reduction in the quality of life often due to prolonged healing time. Several metalloproteinases (MMPs) such as MMP-9 together with neutrophil gelatinase-associated lipocalin (NGAL) appear to be involved in the onset and healing phases of venous ulcer, but it is still unclear how many biochemical… CONTINUE READING
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