Role of mast cells, eosinophils and IL-5 in the development of airway hyperresponsiveness in sensitized mice.

@article{Nagai1996RoleOM,
  title={Role of mast cells, eosinophils and IL-5 in the development of airway hyperresponsiveness in sensitized mice.},
  author={H. Nagai and Shuji Yamaguchi and Yuji Maeda and Hiroyuki Tanaka},
  journal={Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology},
  year={1996},
  volume={26 6},
  pages={642-7}
}
BACKGROUND AND OBJECTIVE In order to study the role of mast cells and IL-5 in allergen-induced airway hyperreactivity in mice, airway responsiveness in WBB6F1-W/Wv mice (mast cell deficient) and the effects of anti-IL-5 monoclonal antibody (NC-17) and three anti-allergic drugs (N-556, ketotifen and amlexanox) on airway hyperreactivity in Balb/c mice were studied. METHODS Mice were immunized with an antigen (ovalbumin; OA) at intervals of 12 days. OA was inhaled 10 days after the secondary… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

Role of immunoglobulin E and mast cells in murine models of asthma.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas • 2003

Similar Papers

Loading similar papers…