Role of loss of heterozygosity on chromosomes 8 and 9 in the development and progression of cancer bladder.

@article{Wahab2005RoleOL,
  title={Role of loss of heterozygosity on chromosomes 8 and 9 in the development and progression of cancer bladder.},
  author={Abdel Hady A. Abdel Wahab and Hamdy I Abo-Zeid and Motawa I El-Husseini and Mohsein Ismail and Akmal M El-Khor},
  journal={Journal of the Egyptian National Cancer Institute},
  year={2005},
  volume={17 4},
  pages={260-9}
}
BACKGROUND Loss of heterozygosity (LOH) in tumor samples is believed to be a marker for the absence of a functional tumor suppressor gene. Non-random chromosome deletion and LOH at specific chromosomal regions are identified in a number of common human cancers including carcinoma of the bladder, which is considered the most predominant cancer in Egypt due… CONTINUE READING