Role of loop entropy in the force induced melting of DNA hairpin.

@article{Mishra2010RoleOL,
  title={Role of loop entropy in the force induced melting of DNA hairpin.},
  author={Garima Mishra and Debaprasad Giri and M S Li and Sanjay Kumar},
  journal={The Journal of chemical physics},
  year={2010},
  volume={135 3},
  pages={
          035102
        }
}
Dynamics of a single stranded DNA, which can form a hairpin have been studied in the constant force ensemble. Using Langevin dynamics simulations, we obtained the force-temperature diagram, which differs from the theoretical prediction based on the lattice model. Probability analysis of the extreme bases of the stem revealed that at high temperature, the hairpin to coil transition is entropy dominated and the loop contributes significantly in its opening. However, at low temperature, the… 
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