Role of local network oscillations in resting-state functional connectivity

@article{Cabral2011RoleOL,
  title={Role of local network oscillations in resting-state functional connectivity},
  author={Joana Cabral and Etienne Hugues and Olaf Sporns and Gustavo Deco},
  journal={NeuroImage},
  year={2011},
  volume={57},
  pages={130-139}
}
Spatio-temporally organized low-frequency fluctuations (<0.1 Hz), observed in BOLD fMRI signal during rest, suggest the existence of underlying network dynamics that emerge spontaneously from intrinsic brain processes. Furthermore, significant correlations between distinct anatomical regions-or functional connectivity (FC)-have led to the identification of several widely distributed resting-state networks (RSNs). This slow dynamics seems to be highly structured by anatomical connectivity but… Expand
Dynamics of large-scale neuronal networks of the human cortex functional connectivity
Spatio-temporally organized low-frequency fluctuations (<0.1 Hz) of blood-oxygen-level-dependent (BOLD) fMRI signal have been intensively investigated as a measure of functional connectivity (FC)Expand
Resting-State Functional Connectivity Emerges from Structurally and Dynamically Shaped Slow Linear Fluctuations
TLDR
A dynamic mean field model is derived that consistently summarizes the realistic dynamics of a detailed spiking and conductance-based synaptic large-scale network, in which connectivity is constrained by diffusion imaging data from human subjects, and it is demonstrated that FC emerges as structured linear fluctuations around a stable low firing activity state close to destabilization. Expand
Resting-State Temporal Synchronization Networks Emerge from Connectivity Topology and Heterogeneity
TLDR
The model consistently approximates the temporal and spatial synchronization patterns of the empirical data, and reveals that multiple clusters that transiently synchronize and desynchronize emerge from the complex topology of anatomical connections, provided that oscillators are heterogeneous. Expand
How delays matter in an oscillatory whole-brain spiking-neuron network model for MEG alpha-rhythms at rest
TLDR
A spiking neuron network model is presented that is able to produce noisy, distributed alpha-oscillations, matching the power peak in the spectrum of group resting-state MEG recordings, and found that the model performs best for propagation delays inside the physiological range. Expand
Dynamic changes in network synchrony reveal resting-state functional networks.
TLDR
In the simulated functional networks, patterns of correlated regional activity clearly arise from dynamical properties that maximize synchrony and variations in synchrony, and results on the fast changes of the level of the network synchrony show how flexible changes in the large-scale network dynamics could be. Expand
Exploring mechanisms of spontaneous functional connectivity in MEG: How delayed network interactions lead to structured amplitude envelopes of band-pass filtered oscillations
TLDR
The results reveal that the structured amplitude envelope fluctuations observed in resting-state MEG data may originate from spontaneous synchronization mechanisms naturally occurring in the space-time structure of the brain. Expand
Modular origins of high-amplitude co-fluctuations in fine-scale functional connectivity dynamics
TLDR
Simulated events in computational models of neural oscillators coupled by anatomical connections derived from maps of the human cerebral cortex suggest that brief, intermittent events in functional dynamics are partly shaped by modular organization of structural connectivity. Expand
Frequency specific interactions of MEG resting state activity within and across brain networks as revealed by the multivariate interaction measure
TLDR
These results demonstrate the existence of consistent, frequency specific phase-shifted interactions on a millisecond time scale between cortical regions within RSN as well as across RSNs. Expand
Computational Models of Dysconnectivity in Large-Scale Resting-State Networks
Abstract Brain activity, on every scale, spontaneously fluctuates, thereby exhibiting complex, dynamic interactions that manifest rich synchronization patterns. In the past decade, many studies haveExpand
Using the Virtual Brain to Reveal the Role of Oscillations and Plasticity in Shaping Brain's Dynamical Landscape
TLDR
This work demonstrates the capability of spike-timing-dependent plasticity (STDP) combined with intrinsic alpha (8-12 Hz) oscillations to efficiently influence learning and shows how alpha-state-dependent STDP alters the local area dynamics from an irregular to a highly periodic alpha-like state. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 46 REFERENCES
Electrophysiological signatures of resting state networks in the human brain
TLDR
This work has identified six widely distributed resting state networks and supports for the first time in humans the coalescence of several brain rhythms within large-scale brain networks as suggested by biophysical studies. Expand
Neuronal correlates of spontaneous fluctuations in fMRI signals in monkey visual cortex: Implications for functional connectivity at rest
TLDR
To the extent that the V1 findings can be generalized to other cortical areas, fMRI‐based functional‐connectivity between remote regions in the resting state can be linked to synchronization of slow fluctuations in the underlying neuronal signals. Expand
Key role of coupling, delay, and noise in resting brain fluctuations
TLDR
In numerical simulation, the dynamics of a simplified cortical network using 38 noise-driven (Wilson–Cowan) oscillators, which in isolation remain just below their oscillatory threshold are studied, indicating the presence of stochastic resonance and high sensitivity to changes in diffuse feedback activity. Expand
Predicting human resting-state functional connectivity from structural connectivity
In the cerebral cortex, the activity levels of neuronal populations are continuously fluctuating. When neuronal activity, as measured using functional MRI (fMRI), is temporally coherent across 2Expand
Neural basis of global resting-state fMRI activity
TLDR
It is reported that the spontaneous fluctuations in the local field potential (LFP) measured from a single cortical site in monkeys at rest exhibit widespread, positive correlations with fMRI signals over nearly the entire cerebral cortex. Expand
Noise during Rest Enables the Exploration of the Brain's Dynamic Repertoire
TLDR
It is shown that comparable resting state networks emerge from a stability analysis of the network dynamics using biologically realistic primate brain connectivity, although anatomical information alone does not identify the network. Expand
Consistent resting-state networks across healthy subjects
TLDR
Findings show that the baseline activity of the brain is consistent across subjects exhibiting significant temporal dynamics, with percentage BOLD signal change comparable with the signal changes found in task-related experiments. Expand
Cortical network dynamics with time delays reveals functional connectivity in the resting brain
TLDR
By tuning the propagation velocity in a network based on primate connectivity, a hypothesis that time delays in the network dynamics play a crucial role in the generation of temporally coherent fluctuations is tested. Expand
Electrophysiological correlates of the brain's intrinsic large-scale functional architecture
TLDR
It is shown in humans that the slow cortical potentials recorded by electrocorticography demonstrate a correlation structure similar to that of spontaneous BOLD fluctuations across wakefulness, slow-wave sleep, and rapid-eye-movement sleep. Expand
The effects of physiologically plausible connectivity structure on local and global dynamics in large scale brain models
TLDR
The results demonstrate that the brain dynamics derived from the CoCoMac database are more complex and biologically more realistic than the one based on the DSI database, and it is proposed that the reason for this difference is the absence of directed weights in the D SI connectivity matrix. Expand
...
1
2
3
4
5
...