Role of liver-infiltrating CD3+CD56+ natural killer T cells in the pathogenesis of nonalcoholic fatty liver disease.

@article{Tajiri2009RoleOL,
  title={Role of liver-infiltrating CD3+CD56+ natural killer T cells in the pathogenesis of nonalcoholic fatty liver disease.},
  author={Kazuto Tajiri and Yukihiro Shimizu and Koichi Tsuneyama and Toshiro Sugiyama},
  journal={European journal of gastroenterology & hepatology},
  year={2009},
  volume={21 6},
  pages={673-80}
}
BACKGROUND/AIMS Natural killer T (NKT) cells have been recently reported to concern with various lipid disorders. The role of NKT cells in the hepatic lipid disorder, nonalcoholic fatty liver disease (NAFLD), has, however, not yet been clarified. To assess the role of NKT cells in the pathogenesis of NAFLD, we analyzed the composition and function of liver-infiltrating cells isolated from liver biopsy specimens of patients with NAFLD. METHODS Specimens from 62 patients with NAFLD were studied… CONTINUE READING