Role of lipoxygenase and cytochrome P-450 in production of endothelium-derived relaxing factors in canine femoral veins.

Abstract

We wished to determine whether the metabolism of arachidonic acid, through lipoxygenase and cytochrome P-450 pathways, is involved in production of endothelium-derived relaxing factor(s) (EDRFs) in canine femoral veins. Veins were removed from anesthetized dogs and cut into rings. Endothelium was deliberately removed from some rings. In separate sets of… (More)

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Cite this paper

@article{Lewis1992RoleOL, title={Role of lipoxygenase and cytochrome P-450 in production of endothelium-derived relaxing factors in canine femoral veins.}, author={Debra Lewis and Virginia M Miller}, journal={Journal of cardiovascular pharmacology}, year={1992}, volume={20 3}, pages={401-7} }