Role of lipid metabolism in hepatitis C virus assembly and entry.

@article{Popescu2009RoleOL,
  title={Role of lipid metabolism in hepatitis C virus assembly and entry.},
  author={Costin-Ioan Popescu and Jean Dubuisson},
  journal={Biology of the cell},
  year={2009},
  volume={102 1},
  pages={63-74}
}
HCV (hepatitis C virus) represents a major global health problem. A consistent body of evidence has been accumulating, suggesting a peculiar overlap between the HCV life cycle and lipid metabolism. This association becomes evident both for the clinical symptoms of HCV infection and the molecular mechanisms underlying the morphogenesis and entry process of this virus. The HCV core-lipid droplets association seems to be central to the HCV morphogenesis process. Moreover, the biogenesis pathway of… CONTINUE READING
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