Role of leukotriene B4 in the pathogenesis of Klebsiella pneumoniae-induced bovine mastitis.

@article{Rose1989RoleOL,
  title={Role of leukotriene B4 in the pathogenesis of Klebsiella pneumoniae-induced bovine mastitis.},
  author={David Rose and Shri N. Giri and Sarah J. Wood and James S. Cullor},
  journal={American journal of veterinary research},
  year={1989},
  volume={50 6},
  pages={915-8}
}
Mastitis was induced in 4 lactating cows by inoculation of Klebsiella pneumoniae (10(7) organisms/ml) via the teat canal. Sterile isotonic saline solution (1 ml) was instilled into designated control quarters via the teat canal. Changes in milk leukotriene B4 and C4 (LTB4, LTC4) concentrations, milk somatic cell counts, and milk bovine serum albumin concentration were monitored over a 24-hour postinoculation period. Milk LTB4 concentration before inoculation in control quarters and quarters… CONTINUE READING

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