Role of leukaemia inhibitory factor (LIF) in rat peripheral nerve regeneration.

@article{Donato1995RoleOL,
  title={Role of leukaemia inhibitory factor (LIF) in rat peripheral nerve regeneration.},
  author={Robert Donato and Surindar S. Cheema and David Finkelstein and Perry F. Bartlett and Wayne A. Morrison},
  journal={Annals of the Academy of Medicine, Singapore},
  year={1995},
  volume={24 4 Suppl},
  pages={94-100}
}
The cytokine leukaemia inhibitory factor (LIF) favours the survival and growth of axons in vitro. The efficacy of this factor in the in vivo model has been the aim of this study. Following nerve transection and immediate entubulation repair in the rat sciatic nerve, this study demonstrated that (1) LIF promotes the growth of a population of axons of greater cross-sectional area after 6 and 12 weeks in comparison to either saline (negative control) or basic fibroblast growth factor (bFGF… CONTINUE READING