Role of leptin and adiponectin in insulin resistance.

  title={Role of leptin and adiponectin in insulin resistance.},
  author={Amita Yadav and Megha A Kataria and Vandana Saini and Anil Yadav},
  journal={Clinica chimica acta; international journal of clinical chemistry},
Adipose tissue is a major source of energy for the human body. It is also a source of major adipocytokines adiponectin and leptin. Insulin resistance is a condition in which insulin action is impaired in adipose tissue and is more strongly linked to intra-abdominal fat than to fat in other depots. The expression of adiponectin decreases with increase in the adiposity. Adiponectin mediates insulin-sensitizing effect through binding to its receptors AdipoR1 and AdipoR2, leading to activation of… CONTINUE READING
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