Role of lean body mass in estimating glomerular filtration rate in Alzheimer disease.

@article{Wetmore2011RoleOL,
  title={Role of lean body mass in estimating glomerular filtration rate in Alzheimer disease.},
  author={James B Wetmore and Robyn A. Honea and Eric D Vidoni and Ammar Almehmi and Jeffrey M. Burns},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={2011},
  volume={26 7},
  pages={2222-31}
}
BACKGROUND The association between estimated glomerular filtration rate (eGFR) and progression of Alzheimer disease (AD), as measured by cognitive decline and brain atrophy, has been infrequently studied. Since AD is characterized by sarcopenia and other changes in body composition, which are known to influence GFR, a determination of how lean mass (LM) affects estimation of GFR in AD patients is important. METHODS Participants were drawn from a prospective longitudinal study of brain ageing… CONTINUE READING