Role of lateral habenula in the regulation of exploratory behavior and its relationship to stress in rats.

The lateral habenula is a major station conveying information between the limbic forebrain and midbrain. Bilateral lesions of the lateral habenula were found to increase exploratory behavior, including locomotor activity, rearing and hole-poke responses in rats. These effects were not due to an augmentation of general motor function, since the animal's… (More)