Role of laminins in physiological and pathological angiogenesis.

  title={Role of laminins in physiological and pathological angiogenesis.},
  author={Patricia Simon-Assmann and Gertraud Orend and Elmina Mammadova-Bach and Caroline Spenl{\'e} and Olivier Lefebvre},
  journal={The International journal of developmental biology},
  volume={55 4-5},
The interaction of endothelial cells and pericytes with their microenvironment, in particular with the basement membrane, plays a crucial role during vasculogenesis and angiogenesis. In this review, we focus on laminins, a major family of extracellular matrix molecules present in basement membranes. Laminins interact with cell surface receptors to trigger… CONTINUE READING