Role of iron-binding proteins and enhanced capillary permeability on the accumulation of gallium-67.

@article{Tzen1980RoleOI,
  title={Role of iron-binding proteins and enhanced capillary permeability on the accumulation of gallium-67.},
  author={K Y Tzen and Zvi H. Oster and Henry N. Wagner and Min-fu Tsan},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={1980},
  volume={21 1},
  pages={31-5}
}
We studied the role of the iron-binding proteins transferrin and lactoferrin and of increased capillary permeability on the accumulation of gallium-67 in rabbits. Intramuscular injection of histamine caused accumulation of gallium-67 (injected i.v. as citrate), and of Tc-99m DTPA, at the i.m. injection site. Normal saline and albumin did not. Intramuscular injection of transferrin or lactoferrin similarly caused Ga-67 uptake. No accumulation of Tc-99m DTPA was observed at the site of… CONTINUE READING

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