Role of intestinal microflora in chronic inflammation and ulceration of the rat colon.

@article{Videla1994RoleOI,
  title={Role of intestinal microflora in chronic inflammation and ulceration of the rat colon.},
  author={Sebasti{\'a}n Videla and Jaime Vilaseca and Francisco Guarner and Antonio Salas and F Treserra and E. Paniagua Crespo and Mar{\'i}a Antol{\'i}n and J. R. Malagelada},
  journal={Gut},
  year={1994},
  volume={35 8},
  pages={1090-7}
}
Bacteria and their products stimulate inflammatory responses. The effects of different antimicrobial regimens (amoxicillin/clavulanic acid, tobramycin, imipenem, vancomycin, metronidazole) were investigated on the course of experimental colitis induced by trinitrobenzenesulphonic acid (TNB) in the rat. On day 7 and 21 after the induction of colitis, matched groups of control and antibiotic treated rats were subjected to colonic dialysis to measure eicosanoid release, and killed for… CONTINUE READING

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Luminal bacteria and bacterial polymers potentiate indomethacin - induced intestinal injury in the rat

  • SW Davis, LC Holt, RB Sartor
  • Gastroenterology
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