Role of interleukin 6 in epithelial hyperproliferation and bone resorption in middle ear cholesteatomas

  title={Role of interleukin 6 in epithelial hyperproliferation and bone resorption in middle ear cholesteatomas},
  author={Jes{\'u}s Buj{\'i}a and Chang Hoon Kim and P. Ostos and . Kastenbauer and Lothar H{\"u}ltner},
  journal={European Archives of Oto-Rhino-Laryngology},
Locally produced pro-inflammatory cytokines are considered to play an important role in the initiation and/or maintenance of inflammatory diseases. In cholesteatomatous lesions there are increased levels of some cytokines and inflammatory mediators like interleukin 1, tumor necrosis factor and colony-stimulating factor, etc. Interleukin 6 (IL-6) can be produced by different cells present in cholesteatoma (e.g. keratinocytes, lymphocytes, fibroblasts and macrophages). Until now, no data have… CONTINUE READING
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