Role of interleukin-10 on hyporesponsiveness of endotoxin during surgery.

  title={Role of interleukin-10 on hyporesponsiveness of endotoxin during surgery.},
  author={Masanori Ogata and Kohji Okamoto and Kenji Kohriyama and Terukazu Kawasaki and Hiroaki Itoh and Akio Shigematsu},
  journal={Critical care medicine},
  volume={28 9},
OBJECTIVE To examine whether surgical stress causes blood cells to lose their responsiveness to endotoxin during surgery. DESIGN Prospective case series. SETTING A university hospital. PATIENTS Sixteen volunteers classified as American Society of Anesthesiologists physical status I-II who were scheduled for elective distal partial gastrectomy. INTERVENTIONS We studied nine patients who underwent elective distal partial gastrectomy. Blood samples for tumor necrosis factor (TNF) and… CONTINUE READING
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