Role of interleukin-1 and prostaglandin in in vitro bone resorption induced by Actinobacillus actinomycetemcomitans lipopolysaccharide.

@article{Ishihara1991RoleOI,
  title={Role of interleukin-1 and prostaglandin in in vitro bone resorption induced by Actinobacillus actinomycetemcomitans lipopolysaccharide.},
  author={Yasunobu Ishihara and Tatsuji Nishihara and Eiji Maki and Tetsuya Noguchi and Toshihiko Koga},
  journal={Journal of periodontal research},
  year={1991},
  volume={26 3 Pt 1},
  pages={155-60}
}
Lipopolysaccharide (Y4 LPS) isolated from Actinobacillus actinomycetemcomitans strain Y4 induced bone resorption in BALB/c mouse calvaria organ culture. The calcium release from LPS-low responsive C3H/HeJ mouse calvaria by Y4 LPS was very low. Indomethacin almost completely inhibited prostaglandin E2 (PGE2) production by Y4 LPS-stimulated BALB/c mouse… CONTINUE READING