Role of interleukin (IL-10) in probiotic-mediated immune modulation: an assessment in wild-type and IL-10 knock-out mice.

@article{Sheil2006RoleOI,
  title={Role of interleukin (IL-10) in probiotic-mediated immune modulation: an assessment in wild-type and IL-10 knock-out mice.},
  author={Barbara Sheil and John Macsharry and Louise O'Callaghan and Alan O'Riordan and Anele Waters and John Morgan and John Kevin Collins and Liam O'Mahony and Fergus Shanahan},
  journal={Clinical and experimental immunology},
  year={2006},
  volume={144 2},
  pages={273-80}
}
While the impact of Bifidobacterium infantis 35624 and other probiotics on cytokines has been shown in established colitis, the effects of B. infantis consumption in pre-inflammation of interleukin (IL)-10 knock-out (KO) mice and on the wild-type (WT) C57Bl/6 mice have not been well demonstrated. The objective of this study was to examine cytokine responses in mucosal and systemic lymphoid compartments of IL-10 KO mice early in disease and to compare with control WT mice. Mice were fed B… CONTINUE READING

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