Role of interferon-gamma release assays in healthcare workers.

  title={Role of interferon-gamma release assays in healthcare workers.},
  author={Jonathan Swindells and S H Aliyu and David Andrew Enoch and Ibrahim Abubakar},
  journal={The Journal of hospital infection},
  volume={73 2},
The advent of interferon-gamma release assays (IGRAs) provides new options for detection of latent tuberculosis infection (LTBI). This is particularly relevant to healthcare workers (HCWs), who are at higher risk of infection, but who have often also been vaccinated. In this article, we discuss the role of IGRAs for the diagnosis of LTBI in various healthcare settings. A search was performed for studies that reported data on IGRAs in HCWs in the last 18 years. Twenty-two studies met the… CONTINUE READING