Role of integrin receptors in manganese-dependent BHK cell spreading on albumin-coated substrata.

@article{Grinnell1991RoleOI,
  title={Role of integrin receptors in manganese-dependent BHK cell spreading on albumin-coated substrata.},
  author={Frederick Grinnell and R. Bruce Backman},
  journal={Experimental cell research},
  year={1991},
  volume={195 1},
  pages={218-23}
}
In manganese-containing medium, tissue cells can spread on albumin and other substrata typically nonadhesive for cells in calcium/magnesium-containing medium. To learn whether integrin receptors play a role in Mn-dependent adhesion, we tested the effects of RGD peptides and polyclonal anti-fibronectin receptor antibodies on BHK cell spreading on fibronectin and albumin-coated substrata. In Ca/Mg-containing medium on fibronectin substrata, the RGD-related peptides GRG-DSP and GRGDS but not RGDS… CONTINUE READING