Role of integration host factor in the regulation of the glnHp2 promoter of Escherichia coli.

@article{ClaverieMartn1991RoleOI,
  title={Role of integration host factor in the regulation of the glnHp2 promoter of Escherichia coli.},
  author={F{\'e}lix Claverie-Mart{\'i}n and Boris Magasanik},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1991},
  volume={88 5},
  pages={1631-5}
}
The glnHPQ operon of Escherichia coli encodes components of the high-affinity glutamine transport system. One of the two promoters of this operon, glnHp2, is responsible for expression of the operon under nitrogen-limiting conditions. The general nitrogen regulatory protein (NRI) binds to two overlapping sites centered at -109 and -122 from the transcription start site and, when phosphorylated, activates transcription of glnHp2 by catalyzing isomerization of the closed sigma 54-RNA polymerase… CONTINUE READING