Role of insulin in development of cancer cachexia in nongrowing sarcoma-bearing mice: special reference to muscle wasting.

Abstract

This study evaluated whether altered insulin metabolism is a key factor behind weight loss during sarcoma growth in nongrowing mice (C57BL/6J). Fasted sarcoma-bearing mice had decreased blood glucose concentrations but unchanged levels of insulin, compared with those in pair-weighed and freely fed controls. During refeeding, insulin levels were… (More)

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@article{Svaninger1987RoleOI, title={Role of insulin in development of cancer cachexia in nongrowing sarcoma-bearing mice: special reference to muscle wasting.}, author={G{\"o}sta Svaninger and Carl Johan Drott and Kent G Lundholm}, journal={Journal of the National Cancer Institute}, year={1987}, volume={78 5}, pages={943-50} }