• Biology, Medicine
  • Published in Nature Reviews Immunology 2015
  • DOI:10.1038/nri3800

Role of innate and adaptive immune mechanisms in cardiac injury and repair

@article{Epelman2015RoleOI,
  title={Role of innate and adaptive immune mechanisms in cardiac injury and repair},
  author={Slava Epelman and Peter Liu and Douglas L. Mann},
  journal={Nature Reviews Immunology},
  year={2015},
  volume={15},
  pages={117-129}
}
Despite the advances that have been made in developing new therapeutics, cardiovascular disease remains the leading cause of worldwide mortality. Therefore, understanding the mechanisms underlying cardiovascular tissue injury and repair is of prime importance. Following cardiac tissue injury, the immune system has an important and complex role in driving both the acute inflammatory response and the regenerative response. This Review summarizes the role of the immune system in cardiovascular… CONTINUE READING

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