Role of inflammation in the pathogenesis of cardiorenal syndrome in a rat myocardial infarction model.

@article{Cho2013RoleOI,
  title={Role of inflammation in the pathogenesis of cardiorenal syndrome in a rat myocardial infarction model.},
  author={Eunjung Melanie Cho and Mina Kim and Yoon Sook Ko and Hee Young Lee and Myeongjin Song and Myung Gyu Kim and Hyoung-Kyu kim and Won-Yong Cho and Sang Kyung Jo},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={2013},
  volume={28 11},
  pages={
          2766-78
        }
}
BACKGROUND Cardiorenal syndrome is now frequently recognized, and the combined dysfunction of heart and kidney increases morbidity and mortality. This study aimed to investigate possible mechanisms that underlie renal damage following heart dysfunction using a rat myocardial infarction model, focusing on the inflammatory pathway. METHODS Rats were randomized into four groups: normal, volume depletion, sham operation and myocardial infarction (MI). MI was induced by the ligation of the left… CONTINUE READING
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