Role of inflammation in the pathogenesis of heart failure with preserved ejection fraction and its potential as a therapeutic target

@article{Glezeva2013RoleOI,
  title={Role of inflammation in the pathogenesis of heart failure with preserved ejection fraction and its potential as a therapeutic target},
  author={Nadezhda Glezeva and John A. Baugh},
  journal={Heart Failure Reviews},
  year={2013},
  volume={19},
  pages={681-694}
}
Heart failure (HF) with preserved ejection fraction (HFPEF) is an increasingly prevalent clinical syndrome with many unresolved issues regarding diagnosis, pathophysiology, and treatment. The major pathophysiological mechanisms underlying HFPEF are known to be fibrosis and reduced ventricular compliance, and hypertension (HTN) is perhaps the most significant risk factor for the development of left ventricular diastolic dysfunction (LVDD). Inflammation is one of the earliest events in cardiac… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

Acute Kidney Injury and Risk of Incident Heart Failure Among US Veterans.

American journal of kidney diseases : the official journal of the National Kidney Foundation • 2018

Acute Heart Failure

Springer International Publishing • 2017

References

Publications referenced by this paper.
Showing 1-10 of 132 references

Causal link between oxidative stress, inflammation, and hypertension.

Iranian journal of kidney diseases • 2008
View 6 Excerpts
Highly Influenced

influence on cardiac form and function

Spinale FG Myocardial matrix remodelling, the matrix metalloproteinases
Physiol Rev 87(4):1285–1342 Heart Fail Rev • 2014

Similar Papers

Loading similar papers…