Role of inflammation in atherosclerosis.

  title={Role of inflammation in atherosclerosis.},
  author={Luigi Giusto Spagnoli and Elena Bonanno and Giuseppe Massimo Sangiorgi and A Mauriello},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  volume={48 11},
Inflammation plays a major role in all phases of atherosclerosis. Stable plaques are characterized by a chronic inflammatory infiltrate, whereas vulnerable and ruptured plaques are characterized by an "active" inflammation involved in the thinning of the fibrous cap, predisposing the plaque to rupture. Although a single vulnerable atherosclerotic plaque rupture may cause the event, there are many other types of plaques, several of which are vulnerable. The existence of multiple types of… CONTINUE READING
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