Role of immune interferon in the monocytic differentiation of human promyelocytic cell lines induced by leukocyte conditioned medium.

Abstract

Conditioned medium (CM) from lectin-stimulated human leukocytes contains factors that induce human promyelocytic cell lines to differentiate along the monocytic pathway. In this report, we show that human promyelocytic cell lines are also induced to differentiate along this pathway by immune interferon (IFN gamma). Various preparations of IFN alpha tested… (More)

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