Role of imatinib in the treatment of pediatric onset indolent systemic mastocytosis: a case report.

@article{Agarwala2013RoleOI,
  title={Role of imatinib in the treatment of pediatric onset indolent systemic mastocytosis: a case report.},
  author={Manoj Kumar Agarwala and Renu George and Vikram Mathews and Poonkuzhali Balasubramanian and Meera Thomas and Sheila Nair},
  journal={The Journal of dermatological treatment},
  year={2013},
  volume={24 6},
  pages={481-3}
}
BACKGROUND Mastocytosis is a sporadic disease characterized by an abnormal accumulation of mast cells (MCs) in single or multiple organs. It has a heterogeneous clinical picture which is a reflection of underlying tissue MC burden, mediators released and the organs involved. Here, the authors report significant symptomatic, cutaneous and systemic response to imatinib in a case of childhood onset indolent D816V KIT unmutated systemic mastocytosis (SM). CASE REPORT A 19-year-old female… CONTINUE READING