Role of hypogastric nerve activity in opossum internal anal sphincter function: influence of surgical and chemical denervation.

@article{Shibamoto1994RoleOH,
  title={Role of hypogastric nerve activity in opossum internal anal sphincter function: influence of surgical and chemical denervation.},
  author={T Shibamoto and Sushanta Chakder and Satish Rattan},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={1994},
  volume={271 1},
  pages={277-84}
}
The exact role of the hypogastric nerve (HGN) in the regulation of basal internal anal sphincter pressures (IASP) and rectoanal reflex (RAR)-induced internal anal sphincter (IAS) relaxation is not known. The studies were performed to investigate the effect of electrical stimulation of HGN (HGNS) on IASP and RAR-induced fall in IASP, simultaneously record the HGN activity (HGNA) and IASP in response to different volumes of rectal balloon distension (RBD) to mimic RAR and determine the neural… CONTINUE READING