Role of hydrosulfide ions (HS-) in methylmercury resistance in Saccharomyces cerevisiae.

@article{Ono1991RoleOH,
  title={Role of hydrosulfide ions (HS-) in methylmercury resistance in Saccharomyces cerevisiae.},
  author={Bun ichiro Ono and Nobuya Ishii and Sumiko Fujino and Isao Aoyama},
  journal={Applied and environmental microbiology},
  year={1991},
  volume={57 11},
  pages={3183-6}
}
Methylmercury-resistant mutants were obtained from Saccharomyces cerevisiae. They were divided into two complementation groups, met2 (homoserine O-acetyltransferase deficiency) and met15 (enzyme deficiency unknown), as reported previously. It was found that met15 was allelic to met17 (O-acetylserine and O-acetylhomoserine sulfhydrylase deficiency). Methylmercury toxicity was counteracted by exogenously added HS-, and both met2 and met17 (met15) mutants overproduced H2S. On the basis of these… CONTINUE READING

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