Role of hydrogen sulfide production in inhibitory action of L-cysteine on isolated porcine irides.

@article{Ohia2010RoleOH,
  title={Role of hydrogen sulfide production in inhibitory action of L-cysteine on isolated porcine irides.},
  author={Sunny E. Ohia and Catherine A. Opere and Emmanuel M. Monjok and Ghislaine Kouamou and Angela M Leday and Ya Fatou Njie-Mbye},
  journal={Current eye research},
  year={2010},
  volume={35 5},
  pages={402-7}
}
PURPOSE To investigate the direct pharmacological actions of L-cysteine, a substrate for the production of H(2)S, on isolated porcine irides in the presence of tone induced by muscarinic receptor stimulation. Furthermore, we examined the underlying mechanism of action of L-cysteine in this smooth muscle. METHODS Isolated porcine iris muscle strips were set up in organ baths containing oxygenated Krebs buffer solution at 37 degrees C. Longitudinal isometric tension was recorded via a grass… CONTINUE READING
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