Role of hepatocyte nuclear factor-4alpha in transcriptional regulation of C1qTNF-related protein 5 in the liver.

Abstract

Recently, we found that C1qTNF-related protein 5 (CTRP5) is involved in glucose and lipid metabolism. However, the transcriptional regulation of CTRP5 is largely unknown. Here we demonstrate the mechanism by which the CTRP5 gene is transcriptionally activated in the liver. CTRP5 is activated by HNF4alpha via the region -206/-167 of the human CTRP5 promoter… (More)
DOI: 10.1016/j.febslet.2010.05.049

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