Role of hemolysin BL in the pathogenesis of extraintestinal Bacillus cereus infection assessed in an endophthalmitis model.

@article{Callegan1999RoleOH,
  title={Role of hemolysin BL in the pathogenesis of extraintestinal Bacillus cereus infection assessed in an endophthalmitis model.},
  author={Michelle C. Callegan and Bradley D Jett and Lynn Ernest Hancock and Michael S. Gilmore},
  journal={Infection and immunity},
  year={1999},
  volume={67 7},
  pages={3357-66}
}
Bacillus cereus is a rare cause of serious human infection but, paradoxically, causes one of the most severe posttraumatic or endogenous infections of the eye, endophthalmitis, which frequently results in blindness. The virulence of B. cereus endophthalmitis historically has been attributed to toxin production. We therefore sought to examine the contribution of the dermonecrotic toxin, hemolysin BL, to the pathogenesis of B. cereus infection in an endophthalmitis system that is highly amenable… CONTINUE READING

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