Role of hemagglutinin cleavage for the pathogenicity of influenza virus.

@article{Steinhauer1999RoleOH,
  title={Role of hemagglutinin cleavage for the pathogenicity of influenza virus.},
  author={David A. Steinhauer},
  journal={Virology},
  year={1999},
  volume={258 1},
  pages={1-20}
}
Although human epidemics of influenza occur on nearly an annual basis and result in a significant number of "excess deaths," the viruses responsible are not generally considered highly pathogenic. On occasion, however, an outbreak occurs that demonstrates the potential lethality of influenza viruses. The human pandemic of 1918 spread worldwide and killed millions, and the limited human outbreak of highly pathogenic avian viruses in Hong Kong at the end of 1997 is a warning that this could… CONTINUE READING
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