Role of gut-brain axis in persistent abnormal feeding behavior in mice following eradication of Helicobacter pylori infection.

@article{Bercik2009RoleOG,
  title={Role of gut-brain axis in persistent abnormal feeding behavior in mice following eradication of Helicobacter pylori infection.},
  author={Premysl Bercik and Elena F. Verd{\'u} and Jane A Foster and Jun Lu and Angela Scharringa and I. R. L. Kean and Lu Wang and Patricia A Blennerhassett and Stephen M. Collins},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2009},
  volume={296 3},
  pages={R587-94}
}
Bacterial infection can trigger the development of functional GI disease. Here, we investigate the role of the gut-brain axis in gastric dysfunction during and after chronic H. pylori infection. Control and chronically H. pylori-infected Balb/c mice were studied before and 2 mo after bacterial eradication. Gastric motility and emptying were investigated using videofluoroscopy image analysis. Gastric mechanical viscerosensitivity was assessed by cardioautonomic responses to distension. Feeding… CONTINUE READING
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Persistence of sensory and eating disturbances after H. pylori eradication in mice

  • P Bercik, L Wang, I Kean, EF Verdu, G Tougas, SM. Collins
  • Gastroenterology 122:
  • 2002
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