Role of glycosylation in function of follicle-stimulating hormone

  title={Role of glycosylation in function of follicle-stimulating hormone},
  author={Dr. Alfredo Ulloa-Aguirre and Carlos M. Timossi and Pablo Dami{\'a}n-Matsumura and James A. Dias},
The oligosaccharide structures of heterodimeric glycoprotein hormones, such as follicle-stimulating hormone (FSH), have been shown to play an important role in the biosynthesis, secretion, metabolic fate, and regulation of potency of the hormone. The oligosaccharide structures attached to each subunit of the protein seem to exhibit distinct roles in some of these functions. Glycans attached to the α-subunit are critical for dimer assembly, integrity, and secretion, as well as for signal… CONTINUE READING


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In Vitro

  • C. Timossi, J. Barrios – de – Tomasi, A. Ulloa–Aguirre
  • Cell . Dev . Biol . Anim .
  • 1998

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