Role of glutamate in a visceral sympathoexcitatory reflex in rostral ventrolateral medulla of cats.

@article{Zhou2006RoleOG,
  title={Role of glutamate in a visceral sympathoexcitatory reflex in rostral ventrolateral medulla of cats.},
  author={Wei Zhou and L W Fu and Stephanie C Tjen-A-Looi and Zhiling Guo and John C. Longhurst},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2006},
  volume={291 3},
  pages={
          H1309-18
        }
}
  • Wei Zhou, L. Fu, J. Longhurst
  • Published 1 September 2006
  • Biology
  • American journal of physiology. Heart and circulatory physiology
The rostral ventrolateral medulla (rVLM) is involved in processing visceral sympathetic reflexes. However, there is little information on specific neurotransmitters in this brain stem region involved in this reflex. The present study investigated the importance of glutamate and glutamatergic receptors in the rVLM during gallbladder stimulation with bradykinin (BK), because glutamate is thought to function as an excitatory neurotransmitter in this region. Stimulation of visceral afferents… 

Figures and Tables from this paper

Role of glutamate in the rostral ventrolateral medulla in acupuncture-related modulation of visceral reflex sympathoexcitation.
TLDR
The data suggest that EA attenuates BK-induced visceral sympathoexcitatory reflexes through opioid-mediated inhibition of Glu's action in the rVLM.
Ionotropic glutamate receptors in the external lateral parabrachial nucleus participate in processing cardiac sympathoexcitatory reflexes.
TLDR
These data are the first to show that NMDA and AMPA ionotropic glutamate receptors in the elPBN play an important role in processing cardiac excitatory reflex responses.
Synaptic and extrasynaptic transmission of kidney-related neurons in the rostral ventrolateral medulla.
TLDR
The results indicate that the GABAergic tonic current may determine the basal tone of firing activity in kidney-related RVLM neurons, and play a role in determining the resting membrane potential, input resistance, and firing rate of RV LM neurons.
Neurogenic Hypotension and Bradycardia Modulated by Electroacupuncture in Hypothalamic Paraventricular Nucleus
TLDR
Data indicate that the hypothalamic paraventricular nucleus processes inhibitory cardiopulmonary reflexes and participates in EA-modulation of the neural-mediated vasodepression and bradycardia.
GABA in nucleus tractus solitarius participates in electroacupuncture modulation of cardiopulmonary bradycardia reflex.
TLDR
Electroacupuncture inhibits PBG-evoked bradycardia and vagally evoked NTS activity through a GABAergic mechanism, likely involving glutamatergic nucleus ambiguus-projecting NTS neurons.
Rostral ventrolateral medullary but not medullary lateral tegmental field neurons mediate sympatho-sympathetic reflexes in cats.
  • S. Barman, H. S. Orer
  • Biology
    American journal of physiology. Regulatory, integrative and comparative physiology
  • 2010
TLDR
Data show that activation of non-NMDA receptors in the RVLM is a critical step in mediating the sympatho-sympathetic reflex.
Cardiovascular responses produced by resistin injected into paraventricular nucleus mediated by the glutamatergic and CRFergic transmissions within rostral ventrolateral medulla
TLDR
It can be concluded that glutamatergic and CRFergic transmissions have crucial contribution to cardiovascular responses produced by resistin, revealing the role of resistin in cardiovascular responses such as metabolic syndrome and hypertension.
...
...

References

SHOWING 1-10 OF 66 REFERENCES
Nociceptin in rVLM mediates electroacupuncture inhibition of cardiovascular reflex excitatory response in rats.
TLDR
In addition to the classical opioid system, nociceptin, through opioid receptor-like-1 receptor stimulation in the rVLM, participates in the modulatory influence of EA on reflex-induced increases in blood pressure.
...
...