Role of glucocorticoid in developmental programming: evidence from zebrafish.

  title={Role of glucocorticoid in developmental programming: evidence from zebrafish.},
  author={Dinushan Nesan and Mathilakath M Vijayan},
  journal={General and comparative endocrinology},
The vertebrate corticosteroid stress response is highly conserved and a key function is to restore homeostasis by mobilizing and reallocating energy stores. This process is primarily initiated by activation of the hypothalamus-pituitary-adrenal axis, leading to the release of corticosteroids into the circulation. In teleosts, cortisol is the primary corticosteroid that is released into the circulation in response to stress. This steroid activates corticosteroid receptors that are ligand-bound… CONTINUE READING
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