Role of gastrin in gastric cancerogenesis in Helicobacter pylori infected humans.

@article{Konturek1999RoleOG,
  title={Role of gastrin in gastric cancerogenesis in Helicobacter pylori infected humans.},
  author={Peter C. Konturek and Stanisław Jan Konturek and Wladyslaw Bielański and Elżbieta Karczewska and Piotr Pierzchalski and Alexandra Duda and Teresa Starzyńska and Krzysztof Marlicz and Tadeusz J. Popiela and Artur Hartwich and Eckhart Georg Hahn},
  journal={Journal of physiology and pharmacology : an official journal of the Polish Physiological Society},
  year={1999},
  volume={50 5},
  pages={857-73}
}
Numerous epidemiological studies demonstrated the association between Helicobacter pylori (H. pylori) infection and gastric cancer but the mechanism of the involvement of H. pylori in gastric cancerogenesis remains virtually unknown. This study was designed to determine the seropositivity of H. pylori and cytotoxin associated gene A (CagA), serum gastrin and gastric lumen gastrin levels under basal conditions and following stimulation with histamine in gastric cancer patients and controls. 100… CONTINUE READING