Role of gap junctions in chronic pain.

@article{Wu2012RoleOG,
  title={Role of gap junctions in chronic pain.},
  author={Ann Wu and Colin Richard Green and Ilva Dana Rupenthal and Gila Moalem-Taylor},
  journal={Journal of neuroscience research},
  year={2012},
  volume={90 2},
  pages={
          337-45
        }
}
Gap junctions are specialized transmembrane channels that allow rapid electrical signalling and direct intercellular communication for maintenance and coordination of normal cellular activities and homeostasis. Although gap junction channels in the nervous system mediate intercellular coupling between glial cells and between neurons, they also contribute to the spread of secondary damage and inflammation under pathological conditions. There is now evidence of the involvement of gap junctions in… CONTINUE READING
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