Role of gammadelta T lymphocytes in the development of Behçet's disease.

  title={Role of gammadelta T lymphocytes in the development of Behçet's disease.},
  author={Noboru Yamashita and Hidetoshi Kaneoka and Shuichi Kaneko and Mitsuhiro Takeno and Kawai Oneda and Hideki Koizumi and Michihiko Kogure and Goro Inaba and Tsuyoshi Sakane},
  journal={Clinical and experimental immunology},
  volume={107 2},
Phenotypic and functional properties of gammadelta T cells, which play an important role in mucocutaneous immunity, were examined to elucidate whether immunological abnormality in Behcet's disease may be related to a specific T cell population. We found that CD45RA+ Vgamma9+ Vdelta2+ gammadelta T cells, which constitute a minor population of gammadelta T cells in healthy individuals, were increased in number in Behçet's disease irrespective of disease activity. This CD45RA+ subset of gammadelta… CONTINUE READING

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