Role of galectin-3 as a receptor for advanced glycosylation end products.

@article{Pricci2000RoleOG,
  title={Role of galectin-3 as a receptor for advanced glycosylation end products.},
  author={Flavia Pricci and Gaetano Leto and Lorena Amadio and Carla Iacobini and Giovanna Romeo and Samantha Cordone and Roberto Gradini and Paola Chiara Barsotti and F. T. Liu and Umberto di Mario and Giuseppe Pugliese},
  journal={Kidney international. Supplement},
  year={2000},
  volume={77},
  pages={
          S31-9
        }
}
The advanced glycosylation end product (AGE)-binding proteins identified so far include the components of the AGE-receptor complex p60, p90 and galectin-3, receptor for advanced glycosylation end products (RAGE), and the macrophage scavenger receptor types I and II. Galectin-3 interacts with beta-galactoside residues of several cell surface and matrix glycoproteins through the carbohydrate recognition domain and is also capable of peptide-peptide associations mediated by its N-terminus domain… CONTINUE READING

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Accelerated diabetic glomerulopathy in galectin-3/AGE receptor 3 knockout mice.

  • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 2001
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