Role of fine‐needle aspiration biopsy and frozen‐section evaluation in the surgical management of thyroid nodules

@article{Caraci2002RoleOF,
  title={Role of fine‐needle aspiration biopsy and frozen‐section evaluation in the surgical management of thyroid nodules},
  author={Pasquale Caraci and S. Aversa and A. Mussa and G Pancani and C. Ondolo and Salvatore Conticello},
  journal={British Journal of Surgery},
  year={2002},
  volume={89}
}
The role of routine frozen section (FS) in the surgical management of thyroid nodules remains uncertain. This study reviewed the role of FS in the presence of an adequate fine‐needle aspiration biopsy (FNAB). 
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56 Citations
Highly Influential Citations
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Background Citations
7
Methods Citations
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Results Citations
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56 Citations

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Citation Type

Diagnostic Accuracy Of Fine-Needle Aspiration Cytology Versus Frozen Section In Solitary Thyroid Nodules
TLDR
FNAC and FS were evaluated in 64 patients who had surgery for a non-toxic solitary thyroid nodule and accuracy of FNAC andFS were assessed by definitive histological section as reference.
The role of fine-needle aspiration biopsy in the dynamic monitoring of patients with nodular goiter
TLDR
This review summarizes recent data on the epidemiology of thyroid nodules, new system of the interpretation of FNA cytology findings, the role of F NA in the dynamic monitoring of benign tumors of thyroid gland, and the application of the new classification system.
Role of intraoperative frozen section in the management of thyroid nodules
TLDR
All patients undergoing frozen section at a typical general surgical department in New Zealand were reviewed to see how often frozen section altered surgical strategy.
Reporting thyroid fine‐needle aspiration: Literature review and a proposal
TLDR
A reporting scheme based on the probability of finding carcinoma on histology is proposed, according to the number of categories in the scheme and the significance of each category.
Role of Fine-needle Aspiration Biopsy and Frozen Section in the Management of Papillary Thyroid Carcinoma Subtypes
TLDR
The recognition of morphologic subtypes of PTC from the FNAB could optimize the selection of patients for intraoperative FS, enhance the preoperative assessment of prognosis, facilitate the surgical planning, and simplify the preparation of postoperative adjuvant therapy.
A meta‐analysis of comparing fine‐needle aspiration and frozen section for evaluating thyroid nodules
TLDR
A meta‐analysis was done to compare sensitivity, specificity, and positive and negative predictive values between FNA and frozen section diagnoses for follicular lesions and found that FNA was much more sensitive but less specific, with lower positive predictive value than frozen section.
Role of frozen section associated with intraoperative cytology in comparison to FNA and FS alone in the management of thyroid nodules.
[The evaluation of thyroid nodules: is routine use of frozen-section examination necessary following preoperative fine-needle aspiration biopsy? ].
TLDR
In view of lower sensitivity and accuracy rates for fine-needle aspiration biopsy, the routine use of frozen-section examination seems to be necessary especially in cases with highly suggestive clinical findings of malignancy.
Role of frozen section analysis in nodular thyroid pathology.
Use and abuse of frozen section in the diagnosis of follicular thyroid lesions
TLDR
Intraoperative consultation including frozen section and intraoperative cytologic examination is most useful in those cases that are diagnosed as suspicious for papillary carcinoma by FNA, because the assessment of nuclear features needed for the definitive diagnosis is possible with intraoperative techniques in a significant number of cases.
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References

SHOWING 1-10 OF 21 REFERENCES
Role of Fine-Needle Aspiration Biopsy and Frozen Section Analysis in the Surgical Management of Thyroid Tumors
TLDR
Results of preoperative FNA had no direct impact on the selection of the surgical procedure in this selected cohort and intraoperative FS added very little to surgical management.
Use of fine-needle aspiration biopsy and frozen section in the management of the solitary thyroid nodule
Relative Accuracy of Fine‐Needle Aspiration and Frozen Section in the Diagnosis of Well‐Differentiated Thyroid Cancer
TLDR
FNA and frozen section are accurate and complementary methods that help in determining the operative management of thyroid masses, but when FNA yields a diagnosis of “follicular neoplasm,” frozen section is unlikely to change this diagnosis.
Assessing the need for frozen sections: still a valuable tool in thyroid surgery.
Evaluation of the fine needle aspiration biopsy in the preoperative selection of cold thyroid nodules
TLDR
By comparing cytologic and histologic diagnoses, preoperative FNAB resulted in the ability to accurately assess the risk of cancer in a thyroid nodule; since 250 nodules were identified as malignant, therisk of a “cold” thyroid nodules being cancer was 4.46% in this series.
Influence of fine-needle aspiration biopsy and frozen section examination on the management of thyroid cancer.
Randomized Prospective Evaluation of Frozen-Section Analysis for Follicular Neoplasms of the Thyroid
TLDR
For the vast majority of patients with follicular neoplasms of the thyroid, frozen section is neither informative nor cost-effective.
Surgical management of thyroid masses: Assessing the need for frozen section evaluation
TLDR
It is concluded that the routine use of intraoperative frozen section may be unnecessary and the use of an adequate preoperative FNA together with sound clinical judgment at time of surgery can adequately guide the extent of surgical resection.
Clarifying the role of fine-needle aspiration cytologic evaluation and frozen section examination in the operative management of thyroid cancer.
TLDR
Fine-needle aspiration cytologic evaluation is extremely valuable in the diagnosis of thyroid cancer and is at least as accurate as frozen section analysis with less morbidity and expense.
Thyroid nodules. Role of fine needle aspiration and intraoperative frozen section examination.
TLDR
FNA provides enough information for determining the extent of thyroid surgery when a diagnosis of cancer is made, however, IFSE should be considered a supplementary procedure when FNA is not positive for cancer.
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